Manas K. Chaudhuri, PhD

Advanced Peptides was founded with Dr. Manas K. Chaudhuri as the Director of Scientific Operations. Dr. Chaudhuri received a Ph.D. in Chemistry from the University of Calcutta, India. His postdoctoral appointments started with Dr. Victor Najjar's Laboratory at the Tufts University School of Medicine, Protein Chemistry Department, Boston, MA, Where Dr. Chaudhuri worked on the synthesis of various types of peptides and radio labeled peptides. While working in the field of synthetic peptide chemistry, Dr. Chaudhuri invented and introduced a novel method of resin cleavage using Trifluoro methane sulfonic acid (TFMSA) to release the peptide from the solid support with simultaneous deprotection of the protecting groups of the side chain as an alternative to anhydrous Hydrofluoric acid (HF). A major work of Dr. Chaudhuri's at Tufts was related to the phagocytosis stimulating peptide Tuftsin and its analogs.

Following his appointment at Tufts, Dr. Chaudhuri joined the Massachusetts General Hospital, Harvard Medical School, as a postdoctoral Research Associate in Dr. Edgar Haber's Group under the laboratory of Dr. James Burton in the Department of Molecular & Cellular Biology. Dr. Chaudhuri left Harvard medical school in 1983 to join the National Institute of Immunology (NII), New Delhi, India as the Head of the Protein & Carbohydrate Chemistry Department. While at the NII, Dr. Chaudhuri took a sabbatical to become a visiting scientist for a year with Professor Jean Rivier at the Peptide Biology Laboratory at the Salk Institute, San Diego, CA. Dr. Chaudhuri designed, manufactured, conjugated, and patented an LHRH analog peptide used as a semi-synthetic vaccine. The drug showed promising results in the atrophy of the prostate and went for clinical trials. For this novel work, Dr. Chaudhuri was awarded the Best Scientist Award from the National Institute of Immunology.

In 1989 he returned to Dr. Haber's Group, working in Dr. Gary Matseuda's Laboratory at Massachusetts General Hospital as a Harvard Fellow in Medicine. He later left with Drs. Haber and Matsueda to join the Princeton University Biology Department, Princeton, NJ as a Research Staff Member. He then returned to Harvard Medical School to run the peptide core facility of the Joslin Diabetes Center, Boston, MA for 5 years. Having worked in various academic peptide fields, Dr. Chaudhuri left to work in industry, working as a Peptide Specialist in manufactured large-scale GMP peptides.

In 1996, Dr. Chaudhuri founded Boston Biomolecules, a custom peptide and large-scale peptide manufacturing company. He ran the company for 12 years as the President and CEO.

Dr. Chaudhuri has a highly varied and experienced background in peptide research and production. This unique combination of skills has allowed Dr. Chaudhuri to interact with customers with a level of specific research oriented analysis that insures their projects are properly planned and executed.